A Pioneer in Integrative Medicine - a memorial for Dr. Stephen Sinatra

Please join me on a special YouTube Live along with a host of esteemed functional medical practitioners as we honor the legacy of Dr. Stephen Sinatra, the consummate integrative cardiologist of all time.

Besides myself, speakers include Dr. Ben Weitz who will moderate the program, Dr. Mark Houston, integrative cardiovascular specialist, nutritionist Dr. Jonny Bowden who co-authored THE GREAT CHOLESTEROL MYTH with Dr. Sinatra, and Dr. Drew Sinatra, naturopath and son of Dr. Sinatra.

Dr. Sinatra was my teacher, mentor, and friend. I truly owe my interest in integrative cardiology to this great man whom we lost too soon. He interested me in Earthing/Grounding, and we performed a small study on the effects of grounding on blood pressure control. The study was eventually published.

I am especially proud of the forward he wrote for my upcoming book, which will be available this fall!

Please click this link to view the program airing on YouTube Live this Tuesday 7/26 at 6PM PST.

This will be a great opportunity for your questions.

ADDENDUM: I am happy to present you with the introduction of our recent podcast from last week, "Honoring the Legacy of a Hero, Dr. Stephen Sinatra." Unfortunately the introduction by our moderator Dr. Ben Weitz was inadvertently left out which was not our intention. This intro is quite important and memorable because it details the career of this great man. This is a link to that beginning part, if you missed it! LINK

Enjoy!
Howard Elkin, MD

Dr Stephen Sinatra


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CONTROVERSIES & ADVANCES IN CARDIOVASCULAR DISEASE - DECEMBER 2021

Attending my first “live” medical conference since COVID-19, I must say that this annual symposium, sponsored by Cedars-Sinai Medical Center, certainly met my expectations for the most part.

Reviewing the role of inflammation and its various triggers as it relates to heart disease was certainly time-honored. Also covered were the controversies of using fish oil, and the highly acclaimed ISCHEMIA trial; should we stent the artery or exhaust medical therapy? After all, the desired result should always be patient outcomes, and not the procedure.

We were updated on the latest in cardiac imaging techniques including echocardiography, CT scanning and CMR (Cardiac Magnetic Resonance), which is MRI with the heart being the targeted image.

If you think women are from Venus and men from Mars, you are correct. It’s not only about the difference in a woman’s presentation that matters but appreciating the role of various risk factors that we don’t generally consider: risks experienced in pregnancy, such as gestational diabetes or pregnancy-induced hypertension, autoimmunity, and depression to name a few. Furthermore, pregnancy totally challenges the cardiovascular system in ways many of us fail to realize.

Being an integrative cardiologist, I like to focus on lifestyle. As expected, this symposium was totally based on the traditional model. Despite this being a full 2-day conference, there was a mere one lecture on nutrition: What Diet is Best for Cardiovascular Health? The speaker recommended a plant-based diet. He outwardly admitted that most nutritional studies are limited in scope, because they tend to be observational in design. He quicky projected slides on a few of these studies, before concluding that the best diet for heart health and longevity was clearly vegan.

My response: Really? Such unequivocal evidence does not exist. There was no mention of the Mediterranean Diet which made headlines years ago with the PREDIMED study. I was majorly disappointed.

My other point of contention was the never-ending argument touting the benefits of statins and new drugs to get the LDL (lousy) cholesterol to levels lower than ever. The concluding recommendation: any patient with any level of coronary disease, as noted on a coronary artery calcium scan, should have LDL cholesterol no higher than 70. Even if the score is a one!  Obviously, drugs would be needed to achieve values this low.

A bit short-sighted, but again this is traditional cardiology.

In summary, I rank this symposium quite favorably despite a few disappointments. I endeavor to take in what I can while appreciating the limitations of traditional cardiology/medicine

VERY IMPORTANT NOTE / DISCLAIMER: I am offering—always—only general information and my own opinion on this site. Always contact your physician or a health professional before starting any treatments, exercise programs or using supplements. ©Howard Elkin MD FACC, 2021

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Dead Bodybuilders

The good, bad and the ugly!

Let’s start with the ugly. 2021 has been a sad year for the professional bodybuilding world. There have been at least 15 deaths in top level professionals, and high-ranking amateurs. Why did this happen, and could it have been prevented?

  • Shawn Roden, aka Flexatron, age 46 died unexpectedly on 11/10/21 from a “suspected heart attack.” He won Mr. Olympia at age 43 (oldest bodybuilder to capture the title). According to reports, Roden had suffered a previous heart attack.

  • Vic “Mr. Big” Richards, age 56, passed away from heart failure on 11/14/21

  • George “Da Bull” Peterson, age 37. He was found dead in hotel room 10/7/21 

  • John “Mountain Dog” Meadows, age 49, died on 8/8/21. He had sustained a major heart attack with permanent heart damage 5/2020 but went back to heavy training. According to reports he “suffered a heart attack due to massive blood clots in his coronary arteries”

  • Megan Elizabeth, age 28, died 8/25/21. Cause of death is unknown

  • Phil Hernon, age 55, died on 8/19/21 due to “sudden decline in health”. He had been on dialysis

  • Orlando Galluci, age 38, died on 8/18/21 of a heart attack. Found dead just before competing in 2021 NPC European Championship

  • Alena Hatvani, age 46, died 8/15/21. The cause of death is unknown. She was getting her final tan and started to faint before competing in Europa Pro2021

  • Sofia Grahm, age 27, died in her sleep on 7/31/21. The cause of death is unknown. She was prepping for a show 

  • Salah Hussein, age 39, died of stroke on 7/21/2021 

  • Jenny Lynn, age 49, died in her sleep on 7/18,2021

  • Melissa Coates, age 50, died on 6/23/21 of unknown cause (8 months prior to her death her leg was amputated “due to blood clots obstructing the blood flow to her lower leg.”

  • Andy Haman, Age 55, died on 3/19/21 due to “complications of elbow joint surgery.” Reports read “pulmonary embolism”

  • Michael “Big Kentucky” Thier, age 50, died on 2/21/21 of kidney failure

  • Richard “Dustin” Cosman, age 39, “passed away in his sleep” on 1/1/21

Death in the line of duty is not new in bodybuilding. The many premature deaths of promising bodybuilders should be a wake-up call to such athletes to be careful. They should be wary of what they consume and generally the kind of lifestyle they lead.

Bodybuilding is indeed a sport. The discipline, focus and sacrifice to succeed in competition is incredible. I should know, because I competed for several years, working my way up the ladder to the Masters National level. I loved it, because it afforded me an opportunity to make a personal goal and to create an action plan to achieve that goal.  Regardless of my placing, I always entered each contest in my best possible condition.

Was it healthy? I can honestly say that is questionable. I mean losing 30 pounds in a span of 12 weeks sounds drastic to me today. Shunning all carbs and fat leaves you with essentially no energy. But to win contests you do what you must do. What I greatly respect is the commitment required. I had and still have that mentality, but I also knew when to draw the line.

What about all these recent bodybuilding deaths. What are the dangers of competitive bodybuilding? Well, it’s not the heavy lifting, vigorous training, or even the diet, despite how drastic that might be. It boils down to misuse of drugs: anabolic steroids, human growth hormone, insulin, and diuretics.

These dangers are not unique to competitors. There are countless athletes and non-athletes alike who have no intention of competing, but who use these drugs to look good, to overcome body dysmorphia, to enhance athletic performance, or simply to achieve that edge. The pity is that such folks often obtain and abuse drugs from unsafe sources and without any medical supervision.

The following are the long-term effects of anabolic steroids on such individuals.

    MOST DAMAGING:

  • Kidney problems or failure

  • Liver damage and tumors

  • Enlarged heart, high blood pressure, and changes in blood cholesterol, all of which can increase the risk of stroke and heart attack, even in young people

  • Increased risk of blood clots

Less dangerous but nonetheless other adverse effects include acne, oily skin and scalp, male pattern baldness, insomnia, mood changes, and tendon ruptures.

Heart disease is the most feared risk of prolonged steroid use. The following constitutes the complications that may be encountered:

  • Abnormalities in blood lipids (total cholesterol, LDL (lousy cholesterol) and HDL (healthy cholesterol)

  • Hypertension

  • Coagulation disorders (such as platelet aggregation, leading to blood clots)

  • Cardiomyopathy (often a heart that is either thickened, enlarged and often with impaired relaxation, known as diastolic dysfunction)

  • Myocardial infarction and fatal arrhythmias that could lead to sudden cardiac death

I have evaluated several top-level pro bodybuilders and fitness competitors in my practice. Because of their awareness of these cardiac and other risks, they have done quite well as a whole. However, most competitors never see a physician.

I have no details as to the medical history on any of the individuals listed above. However, I venture to say that most of these fatalities could have been prevented. Let’s face it; how often do we see heart attacks, strokes, and both heart and kidney failure in the healthy young adult population?

For those who choose to use steroids, I recommend practicing prevention to mitigate the cardiac risks secondary to anabolic steroids.

WHAT ABOUT INSULIN?

Insulin is an anabolic hormone which promotes storage of nutrients such as carbohydrates in the form of glycogen and amino acids for protein synthesis. Therefore, such nutrient storage fuels the muscles and boosts muscle mass

Insulin abuse is the latest deadly trend. Bodybuilders use it -- often in combination with steroids -- to pump their muscles full of staying power. It's estimated that one in four steroid abusers also take insulin.

The insulin helps feed muscles during intense exercise, prevents muscle breakdown, and helps performance. The International Olympic Committee bans insulin. However, it's impossible to detect. Cheaters can take it just before an athletic competition and not get caught.

 Insulin just might boost athletic performance. And it just might kill. Bodybuilders are generally insulin sensitive as it is. By taking exogenous insulin and not knowing how and when to ingest carbs can seriously lower blood sugar. COMA and DEATH can result.

Insulin also promotes fat storage.  As powerful as insulin is, it also has a major flaw. It can build up fat cells and muscle cells in equal measure. If you eat sugary carbs at the same time as you eat fat, your body transports the carbs into the cells right along with the fat.

HUMAN GROWTH HORMONE (HGH)

Combining steroids with HGH is certainly not new. While steroids are best known for increasing muscle mass and strength, HGH, on the other hand, impacts body composition. It directly promotes fat burning. It is involved with the turnover of muscle tissue, which is important for adding lean muscle mass. HGH helps to maintain, build, and repair healthy tissue in the brain and other organs. This hormone can help to speed up healing after an injury and repair muscle tissue after exercise. This helps to build muscle mass, and boost metabolism,

While all this sounds great, there are some major drawbacks:

  • Carpal tunnel syndrome.

  • Increased insulin resistance.

  • Type 2 diabetes.

  • Swelling in the arms and legs (edema)

  • Joint and muscle pain.

  • For men, enlargement of breast tissue (gynecomastia)

  • Increased risk of certain cancers.

If you’ve observed top level pro bodybuilders lately, you might notice that their abdomens are grossly distended, despite having ripped abs. This is anything but aesthetically pleasing and is a result of overuse of HGH and insulin. Indeed, the liver and spleen can enlarge as well as the kidneys and loops of bowel. What’s worse is that these changes are generally permanent. Don’t expect internal organs to shrink back to their normal size once HGH is discontinued!

DIURETICS:

Competitive bodybuilders strive for that hard shredded, dry look at contest time. Diuretics are often used to achieve this goal. However, severe dehydration, kidney failure, electrolyte derangements, cardiac arrhythmias and sudden death can result. Talking about death in bodybuilding, most hospitalizations and deaths are, in fact, overwhelmingly due to the use and abuse of diuretic supplements.

NOW THE GOOD!

The focus thus far in this article may seem negative, but being prompted by the recent deaths in bodybuilders, I felt the need to come forward and bring this discussion to light.

But there is mostly good in bodybuilding and strength training. I may be a cardiologist and I do recommend aerobic exercise, but if I only had a few minutes to train, I would favor weight training.

Weight training helps increase your strength while improving the tone and amount of muscle you have. This is vital for long-term health since inactive adults lose anywhere between 3-8% of their muscle mass per decade.

Resistance training for the older adult, age 65-and above has been extensively studied. The health benefits are well known and include the following:

  • Increases muscle strength and endurance.

  • Increases muscle mass which translates into improvements in functional capacity (combatting sarcopenia or muscle wasting).

  • Increases bone density (combatting osteoporosis).

  • Increases insulin sensitivity (combatting diabetes and metabolic syndrome).

  • Mitigates pain from arthritis.

  • Improves sleep.

  • Reduces depression.

There are additional cardiac benefits of weight training that are becoming increasingly well appreciated.

In conclusion, weight or resistance training should be a permanent component of your exercise regimen. Each one of us could benefit.

As your own Medical Advocate, choose what’s best for your individual health and wellness. You will never go wrong with strength training.

VERY IMPORTANT NOTE / DISCLAIMER: I am offering—always—only general information and my own opinion on this site. Always contact your physician or a health professional before starting any treatments, exercise programs or using supplements. ©Howard Elkin MD FACC, 2021

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Covid 19 Vaccines & Myocarditis: Should We Be Concerned? A Cardiologist Perspective

There has been a lot of hoopla lately regarding a possible connection between the COVID -19 vaccine and myocarditis in young people under the age of 30. Is there truly a causal link here and how concerned should we be?

How did this evolve?

In early June, the CDC issued a note to healthcare providers raising awareness of myocarditis and pericarditis after vaccination, particularly in younger males. That guidance stated that, since April, there had been an increase in reports of myocarditis and pericarditis after getting the Pfizer or Moderna vaccines, but that there had not been a similar reporting pattern following the Johnson & Johnson vaccine.

The CDC's "clinical considerations" update followed a May 24 report from Advisory Committee on Immunization Practices (ACIP)'s COVID-19 Vaccine Safety Technical (VaST) Work Group, which found "a higher number of observed than expected myocarditis/pericarditis cases in 16- to 24-year-olds" in Vaccine Adverse Event Reporting System (VAERS) data within 30 days of dose 2, though it didn't see the same pattern in data from Vaccine Safety Datalink.

The data is a bit confusing, but obviously there needs to be more surveillance as more persons in these younger age groups get vaccinated. Important meetings will be held this week as the CDC’s vaccine safety team provides more data on myocarditis and pericarditis.

The country saw 275 cases of myocarditis from December 2020 to May 2021 among more than 5 million vaccinated people, according to Reuters. Most of these patients spent no more than 4 days in the hospital, and 95% of cases were classified as mild. The association appeared strongest among men ages 16 to 19 and was more common after the second dose.

Symptoms of myocarditis and pericarditis include chest pain, shortness of breath or palpitations. In most cases, patients responded well to medications and rest, and their symptoms improved quickly.

How to make sense of it all?

Though a causal relationship between vaccination and myocarditis has yet to be established, the possibility for a relationship does exist and obviously we need more data. In the interim, we continue to recommend vaccinations because the benefits outweigh the risks.

We must remember that there have been more then 4 million COGVID-19 cases in children under the age of 18 that have resulted in over 15,000 hospitalizations and between 300 and 600 deaths.

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My take on all this:

Don’t overthink these findings. Have faith that true science won’t fail us. We will learn more in the coming weeks. Also be aware of the anti-vaxer activists who attempt to spread disinformation about COVID-19 vaccines.

There exists a huge database for detecting rare but potentially serious vaccine side effects. Epidemiologists consider this a starting point in their search for causal events. Known as the Vaccine Adverse Event Reporting System, or VAERS, this database has played a major role in the spread of misinformation about COVID-19 vaccines.

As your own Medical Advocate, weigh your options carefully before making judgment. It’s all about staying in the driver’s seat when it comes to your health.

VERY IMPORTANT NOTE / DISCLAIMER: I am offering—always—only general information and my own opinion on this site. Always contact your physician or a health professional before starting any treatments, exercise programs or using supplements. ©Howard Elkin MD FACC, 2021

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New Drugs: GameChangers?

The FDA approved 2 new medications in the last few days. Are these additions truly medical advancements, otherwise known as “gamechangers”? What about the drawbacks?

DRUG #1

A 2.4 mg /week subcutaneous dose of the glucagon-like peptide (GLP-1) receptor agonist semaglutide (Wegovy by Novo Nordisk) has been approved for weight loss. Indications: to be used as an adjunct to a reduced-calorie diet and increased physical activity for adults with obesity.

This medication works by reducing hunger while promoting feelings of fullness. It is being hailed as a paradigm changer in the war against weight loss.

The favorable decision is based on results of a four phase 3 clinical trials that tested the drug’s efficacy and safety in more than 4,500 patients who were randomized to receive a reduced calorie meal plan and an exercise program OR the lifestyle intervention plus semaglutide. Studied subjects attained a 15-18% weight loss over 68 weeks.

What’s interesting is that this is not a new drug. Under the name of Ozempic, it is used in control of type 2 diabetes. However, the dose studied for weight loss is significantly higher.

Drawbacks include GI side effects including nausea, vomiting, and epigastric distress from fullness. Side effects such as abdominal cramping, constipation and diarrhea can be exacerbating symptoms in those who suffer from irritable bowel syndrome. Then there is the subject of cost which is estimated to be about $1350 which more than likely will not be covered by insurance.

This is not a small deal. With 70% of the US population overweight and 42% obese, we are clearly losing the battle of the bulge. There may well be a role for this medication (first weight loss drug introduced since 2014). The hope is that it might also cut down on attendant diseases such as heart disease, hypertension, lipid abnormalities, cancer and diabetes often seen in the obese population.

My view: I don’t think of this as a miracle drug, but it could represent a paradigm shift in weight loss drugs where we target the gut as opposed to the brain. However, this shift should NEVER be a solution without altering lifestyle (diet and exercise), which remains my modus operandi.

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DRUG #2

A 170 mg monthly intravenous drug aducanumab (Aduhelm by Biogen), has been approved for Alzheimer’s disease. This is a monoclonal antibody that selectively binds to accumulated amyloid plaque in the brain (a hallmark of Alzheimer’s disease).

This medication is certainly more controversial, than the weight loss drug discussed above. Two trials EMERGE and ENGAGE were terminated 3/2020 when it became obvious that the drug was unlikely to outperform placebo. Then in 11/20, in an ongoing battle with Biogen, the FDA overwhelmingly voted against the drug, after a second analysis determined that positive results were seen in only one of the two trials.

CONFUSED YET?

The FDA eventually approved the drug earlier this week through the agency’s accelerated approval pathway (a fast-track method). This allows the approval of a drug for serious conditions that fill an unmet need. This approval assumes but does not prove that the drug will produce a clinical benefit. The endpoint here is the ability for the drug to reduce beta-amyloid in the brain.

What we know is that there have been several anti-amyloid drugs in the past that reduced plaque but showed no benefit on cognition.

Well, Aducanumab might have been approved, but Biogene is required to conduct a post-approval trial to demonstrate clinical benefit. If expectations are not met, the FDA may withdraw the drug’s approval.

Does any of this make sense? Here a drug is marginally approved via fast track after being denied such status just a few months prior. And the conditions for ultimate approval are great.

Aducanumab is to be administered intravenously every 4 weeks at a cost of about $56,000 per year. Not included is the price of ongoing MRIs, which the FDA advises to monitor patients.

Now accelerated approval based on ongoing clinical benefits requiring a confirmatory trial is not new. It’s been used in the past for cancer drugs.

The problem as I see it is that functional medical practitioners like myself see Alzheimer’s disease as a multipronged disease. There more than likely will never be a medication that will either reverse the disease or stop it in its tract. Many believe that the deposition of amyloid plaque in the brain is more likely the body’s response to quell ongoing inflammation.

My view: There appears to be too much hope on a drug to alter the course of Alzheimer’s disease. There is more to this disease than amyloid plaque. Let’s not forget about diet, exercise and lifestyle. There are several integrative neurologists that believe Alzheimer’s can actually be prevented.

So here you have 2 new medications approved within one week. You will no doubt be hearing a lot about these soon. Keep an open mind. As a Medial Advocate, do your part to stay in the driver’s seat as it relates to your health.

 Links to articles referenced:
A Drug to Treat Alzheimer's Was Approved. Now What?
FDA Approves 'Game Changer' Semaglutide for Weight Loss

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What Harm Can a Few Daily Sips Do?

Although light drinking has been touted as beneficial by many, a large observational study recently reported that small amounts of alcohol were linked to a common heart rhythm disturbance (arrhythmia) known as atrial fibrillation (Afib).

This is no small deal, as Afib is the most common arrhythmia in those over the age of seventy. However, it has increasingly been noted in younger folks as well. As a matter of fact, two of my best friends had refractory a fib in their early 50s, eventually requiring a definitive procedure known as an ablation. Furthermore, a 29-year-old athletic male patient of mine recently underwent an ablation for the same problem.

ABOUT THIS STUDY: Increase risk of a fib was observed in just one daily drink containing 12 g ethanol, whether the beverage was 120 mL wine (four-fifths of a standard glass, 330 mL of beer (nearly a can’s worth), or 40 mL of spirits (roughly one shot). Findings were consistent for both men and women.

Even very low alcohol consumption, at a mere 2 g per day, was marginally associated with risk of a fib over nearly 14 years of follow-up. (see link below from the European Heart Journal, January 2021).

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This study from Hamburg, Germany pooled five community cohorts from Europe totaling 100,092 subjects. Based on questionnaires and hospital records, 5,854 individuals developed Afib over a median period of 13.9 years.

Limitations of the trial included reliance on self-reported drinking patterns in an observational study. We know from a randomized trial in 2019 that a reduction in alcohol intake led to a reduction in a fib recurrence. The current study adds that lowering alcohol consumption may be important for both prevention and management of Afib.

Further reading for those interested: Link to the study published in the European Heart Journal, Jan 2021: Alcohol consumption, cardiac biomarkers, and risk of atrial fibrillation and adverse outcomes

To learn more about this troublesome arrhythmia, it’s adverse consequences, and identifying those at risk, please join me for my next YouTube Live on Thursday February 4th at 7:00 pm PST. Simply subscribe to my channel: The Medical Advocate, Howard Elkin, MD

VERY IMPORTANT NOTE / DISCLAIMER: I am offering—always—only general information and my own opinion on this site. Always contact your physician or a health professional before starting any treatments, exercise programs or using supplements. ©Howard Elkin MD FACC, 2020

berkeley stewart
New Exercise Recommendations from WHO: No Rest For the Weary!

We all know how important exercise is for the heart, the brain and for a myriad of other reasons.

Recently published in the British Journal of Sports Medicine, the World Health Organization (WHO) has updated its guidelines for exercise. Indeed, these are evidence-based public health recommendations.

Clearly a departure from the last set of guidelines in 2010, what is now recommended is 150-300 minutes of moderate exercise/week, 75-150 of vigorous exercise/week, or some combination of the two. The previously published guidelines recommended a total of 150 minutes/week. Thus, what we have now is a major upgrade.

Older adults, including those with chronic conditions and living with disability are not exempt from exercise. In fact, activities that emphasize functional balance and strength should be performed three or more days a week at moderate or greater intensity.

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Exercise for children and adolescents was also upgraded. Now recommended is an average of 60 minutes per day of moderate to vigorous intensity aerobic physical activity throughout each week.

Also included were recommendations for pregnant and postpartum women who should aim for a minimum of 150 minutes of moderate- intensity aerobic activity per week.

Getting in the requisite amount and intensity of exercise in this era of COVID-19 and gym closures is clearly a challenge. Indeed, but some exercise is better than none, and more is definitely better! 88% of Americans are metabolically unhealthy. This alone underscores the need for lifestyle alteration.

Less than 5% of adults participate in 30 minutes of physical activity each day; only one in three adults receive the recommended amount of physical activity each week. Only 35-44% of adults 75 years or older are physically active, and only 28-34% of adults ages 65-74 are physically active.

Despite current challenges, we should all strive to maintain our physical well-being through diet and exercise. These new guidelines, which may seem unattainable to many, are a great reminder of what we need to achieve to obtain optimal health and wellness.

Further reading for those interested: an open source paper from The British Journal of Sports Medicine explaining the development of the guidelines: World Health Organization 2020 guidelines on physical activity and sedentary behaviour

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12th Annual Orange County Symposium for Cardiovascular Disease Prevention: Crossroads in Cardiovascular Disease Prevention

As an integrative cardiologist practicing functional medicine, I’m always excited about learning everything I can about prevention. At this virtual conference, I learned a few good pearls, but I was hoping for more!

The topics were clearly of interest: assessing cardiovascular risk, dealing with LDL-Cholesterol over 210 mg/dl, using fish oil in clinical practice, strategizing prevention in women, and dealing with the aging population. However, from the onset it was obvious that the pharmaceutical approach was the holy grail.

Now in my 35 years of active practice, I have treated countless ill patients with life-saving drugs. I’m very aggressive about using meds when the science points to their efficacy. My background is deeply entrenched in traditional cardiology. In fact, I still take regular emergency call at my local hospital to intervene in those who present with acute heart attacks.

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However, this was billed as a preventative program. What I found disappointing was that there was little voiced about lifestyle. It was mentioned, but in word only. In all fairness, the overall emphasis was on secondary prevention (or treating those with known disease who are automatically stratified as being high risk). Such treatment clearly mandates a more aggressive approach. But many of the speakers advocated LDL-C levels of 30 or lower, or what I call “lower is better”. I personally do not support this concept.

There was a particularly good presentation on the use of nutraceuticals in cardiac patients. Mentioned was the use of berberine, bergamot, fish oil and turmeric. I also learned a new role of niacin for the treatment of nonalcoholic fatty liver disease (NAFLD), a disease entity of increasing incidence.

There was a single lecture on nutrition. The presenter essentially espoused the dogma of the American Heart Association (AHA); an extremely low saturated fat diet, less than 8% of all calories. Such thinking has been since debunked by many. (see “what’s new” from July 2020 at www.heartwise.com).

Any benefit of a low carb diet, ketogenic diet, or any form of fasting was quickly dismissed, despite documented benefits in the medical literature.

The use of hormone replacement therapy in menopausal/post-menopausal women was discouraged because of potential cardiac risks. This was most probably based on the results of the Women’s Health Initiative, released in 2002. What was never mentioned was the use of bioidentical hormone replacement, which has a myriad of benefits for both heart health and bone health.

It’s interesting but disappointing how a university sponsored educational event can be so one sided and seemingly dated. However, I endeavor to take it all in and utilize both my traditional training and what I’ve learned in integrative cardiology. It’s about knowing which hat to wear when.

PS Contrary to the symposium’s flier photo, there wasn’t any mention about running, walking or any form of exercise!

VERY IMPORTANT NOTE / DISCLAIMER: I am offering—always—only general information and my own opinion on this site. Always contact your physician or a health professional before starting any treatments, exercise programs or using supplements. ©Howard Elkin MD FACC, 2020

berkeley stewart
BISPHENOL  A (BPA) EXPOSURE & RISK OF DEATH
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Many of us know that the ubiquitous chemical bisphenol A (BPA) found in plastics and epoxy resins is endocrine- disrupting, and is clearly antithetical to good health. In a recently-released cohort study of 3,883 adults in the United States, subjects with the highest urinary levels of this chemical had a higher risk of death over a 10 year period.

Those with the highest levels had a 49% increased risk of all-cause mortality, and a 46% increased risk of cardiovascular risk mortality.

This news is hardly unexpected given the populace of plastics in our lives. We are not just talking about the obvious plastics, but also many commonly used consumer products such as compact discs, medical devises, and dental sealants and composites. 

Endocrine-disrupters, such as BPA disrupt our hormonal balance and can lead to obesity, diabetes and metabolic syndrome. Exposure to BPA can accelerate coronary heart disease, and induce cardiac arrhythmias. 

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The news is not good. We clearly need to limit the use of plastics and do a better job of recycling.  Moreover, we certainly need and deserve a government that works for the people, and who earnestly endeavors to protect us from environmental hazards.

You can read the original article from JAMA Network clicking HERE.

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ENDING THE WAR ON SATURATED FAT

For years saturated fat has been vilified in the cardiology literature as well as by prestigious professional organizations such as the American Heart Association (AHA ). But many of us have questioned these motives, as we do not believe that universally restricting consumption of saturated fat is scientifically based. 

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As a matter of fact, there is no true evidence that dietary fat, which generally contains significant amounts of saturated fat, has any harmful cardiovascular consequences. This is in contradistinction to what has been disseminated over the past fifty years.

Recently, a “State-of-the Art Review” published in the prestigious Journal of the American College of Cardiology provided evidence to the contrary which supports my view and the view of many others in the nutritional field. 

These are some of the highlights:

  • Most recent meta-analyses of both randomized trials and observational studies found no beneficial effects of reducing saturated fat on cardiovascular disease and total mortality. Instead, protective effects were found against stroke.

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  • Although saturated fat increases low-density cholesterol (LDL), this is not due to increased levels of small dense LDL particles, but rather larger fluffy LDL particles, which are much less strongly related to cardiovascular risk. 

  • Whole-fat dairy, unprocessed meat, eggs and dark chocolate are all saturated fat rich foods that are not associated with increased cardiac risk.

  • The totality of available evidence does not support limiting these foods.

LET’S DEBUNK THE MYTH ABOUT SATURATED FAT!

Link to the Journal of the American College of CardiologySaturated Fats and Health: A Reassessment and Proposal for Food-based Recommendations: JACC State-of -the-Art Review

Click here for full PDF of the Study "Fats and Health: A Reassessment and Proposal for Food-based Recommendations: JACC State-of -the-Art Review" from the Journal of the American College of Cardiology.

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LONG-HAULERS AND COVID 19: WHAT’S MILD?

Seriously, I feel as if I’ve written enough about COVID-19. Most of you are probably sick and tired hearing about this topic. However, because this illness is so rampant and because it has claimed the lives of over 110,000 Americans in a very short time, there is a lot more that we simply need to know.

Firstly this virus is very fickle. How it affects individual patients varies greatly. Initially we thought the major cause of death and disability was Acute Respiratory Distress Syndrome (ARDS). Then we learned that the ARDS caused from this virus was heterogeneous, and varies from patient to patient. This can undoubtedly affect treatment.

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Then we learned that the illness has many cardiac manifestations with presentations that actually simulate an acute heart attack. Next we became aware that this is a disease of hypercoagulability where the tendency for blood clotting is huge. Clots have been found in the lung, the kidneys, the brain, and the carotid arteries. Suddenly we learn that young folks are presenting with acute strokes.

This recent article from The Atlantic gives us a different and scary perspective from survivors of COVID-19 who never required admission to ICU and who never went on a ventilator. These are among cases typically classified as “mild”. However, such folks have wrestled with symptoms that have lasted at least a month, if not two or three.

Yes, such cases may be considered mild when compared to those dying alone in hospitals. However, they have been plagued by extreme fatigue, difficulty with concentration, exercise, and performance of simple tasks. Most are young and were previously considered fit and healthy.

Realizing that this group of patients, known as “long- haulers” may well represent a minority, it nonetheless gives credence that this illness can be manifested in several different ways.

Indeed we will continue to learn more and more as time goes by.

Link to The Atlantic Article “Covid-19 Can Last for Several Months”

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INTRODUCING IMMUNOWISE

We've all been inundated with the grim facts and statistics about COVID-19. I've talked and blogged about this repeatedly. My wish is for all of us to take this opportunity and give thanks to what we have versus lament over what we cannot control.

THERE IS NO BETTER TIME THAN NOW!
To order, or arrange a nutritional evaluation, email our nutritionist Kristine Solomon at kristine@heartwise.com or call the office at (562) 945-3753.

In the next several weeks all 50 states will be "opening up" in one way or another. Exposure to COVID-19 and other pathogens won't  just wither away. We followed the requisite social distancing, etc. But we can't live that way forever. If you haven't already started practicing prevention, what are you waiting for ?

Working on optimizing your immune system should be number 1 on your list.  Most  patients who fare poorly are generally not healthy. They suffer from hypertension, heart disease, diabetes and obesity. It doesn't have to be that way.

I've talked about diet, exercise , hydration , sleep and stress reduction. Those are key.

I've gone one step further and created IMMUNOWISE. One capsule 3/day will help promote a healthy immune system. There are lots of supplements out there. My goal was to provide  an affordable product comprised of solid ingredients in appropriate doses that have been scientifically proven to be of benefit.

Please read the below fact sheet and feel free to contact  our clinical nutritionist Kristine Solomon at kristine@heartwise.com for any orders and/or inquiries. Office phone: (562) 945-3753.

Here's to your health; today and for always,

Howard Elkin MD

WHAT IT IS:

  • A custom formulated high-quality blend of powerful immunity boosting and anti-viral ingredients.

WHY YOU NEED IT:

  • Important for patients wanting to keep their immune systems on high alert to fight off infections and viruses and reduce duration of illness.

  • All Natural, gluten-free, dairy-free, non-GMO

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Vitamin C

Vitamin C contributes to immune defense by supporting various cellular functions of both the innate and adaptive immune system. Vitamin C accumulates in phagocytic cells, such as neutrophils, and can enhance chemotaxis, phagocytosis, generation of reactive oxygen species, and ultimately microbial killing. Supplementation with vitamin C appears to be able to both prevent and treat respiratory and systemic infections. Vitamin C has been used in hospital ICUs to treat COVID-19 infection.

Vitamin D

Activated vitamin D,1,25(OH) D, a steroid hormone, is an immune system modulator that reduces the expression of inflammatory cytokines and increases macrophage function. Vitamin D also stimulates the expression of potent antimicrobial peptides (AMPs), which exist in neutrophils, monocytes, natural killer cells, and epithelial cells of the respiratory tract. Vitamin D increases anti-pathogen peptides through defensins and has a dual effect due to suppressing superinfection. Evidence suggests vitamin D supplementation may prevent upper respiratory infections.

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Zinc- Zinc contributes to immune defense by supporting various cellular functions of both the innate and adaptive immune system. There is also evidence that it suppresses viral attachment and replication. Zinc deficiency is common, especially in those populations most at risk for severe COVID-19 infections, and it is challenging to accurately diagnosis with laboratory measures. Supplementation with zinc is supported by evidence that it both prevents viral infections and reduces their severity and duration. Moreover, it has been shown to reduce the risk of lower respiratory infection, which may be of particular significance in the context of COVID-19

Quercetin- Quercetin has been shown to have antiviral effects against both RNA (e.g., influenza and coronavirus) and DNA viruses (e.g., herpesvirus). Quercetin has a pleiotropic role as an antioxidant and anti-inflammatory, modulating signaling pathways that are associated with post-transcriptional modulators affecting post-viral healing.

N-Acetylcysteine (NAC)

N-acetylcysteine promotes glutathione production, which has been shown to be protective in rodents infected with influenza. In a little-noticed six-month controlled clinical study enrolling 262 primarily elderly subjects, those receiving 600 mg NAC twice daily, as opposed to those receiving placebo, experienced significantly fewer influenza-like episodes and days of bed confinement.

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COVID-19 AND BLOOD PRESSURE MEDS?

There is no question that COVID-19 has turned our world upside down, and has remained the number 1 health concern for essentially all of us. However, we never doubted that certain classes of blood pressure medications would be suspect for worsening morbidity and mortality.

ACE inhibitors (eg. lisinopril, accupril, captopril, enalapril, benazepril,etc.) and ARBs or angiotensin receptor blockers ( losartan, valsartan, olmesartan, etc), are amongst the most commonly used meds for hypertension. They certainly constitute the most widely used meds in my cardiology practice. However, with the pandemic of Coronavirus COVID-19, these meds have recently come under scrutiny. 

Concern for these drugs grew out of recent observational Chinese data showing greater morbidity  and mortality among patients with hypertension who went on to develop COVID-19. However experts have come forth reporting that there was no adjustment for certain variables. The validity of the Chinese observation is clearly being questioned. The current consensus is that the data is simply not there. 

Most cardiologists, including myself do not recommend changing to other medications to control blood pressure; even in the presence of COVID-19. There is definite potential harm in doing so. Firstly, there is no simple formula in switching from one class of medications that have successfully controlled a patient’s blood pressure to a new class. Why go from a well-tolerated class and dose of a specific mediation to an unknown? This could easily lead to worsening blood pressure, or drug toxicities due to changing to an entirely different class. From my perspective, this is not a time to attempt trial and error. 

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The other concern is losing the positive effects of ACEs and ARBs that are specific to this class of meds. These include preserving kidney function in those with diabetic kidney disease, and maintaining cardiac function in those with a history of congestive heart failure.

Fear of using these drugs stems from up-regulation of ACE2 receptors, possibly increasing viral entry into cells in the laboratory.  But we do not know the effect in the context of the human body.

In conclusion, we lack prospective data on the use of these commonly used Bp meds and their impact on COVID-19 patients. From the viewpoint of The Medical Advocate, I say stick with what works. 

Hypertension and cardiovascular disease remain the highest risk for mortality in those afflicted with COVID-19. Changing medications at such a vulnerable time is simply not recommended. It boils down to risks versus benefits. The potential risk of changing medications is outweighed by the benefits of remaining on these medications that clearly work .    

You can read the original article from TCTMD by clicking HERE.

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A FUNCTIONAL MEDICINE PRACTITIONER'S PERSPECTIVE ON COVID-19

Coronavirus  COVID-19 is  the hottest topic these days, and for good reason;  it's become a pandemic that has completely changes our lives.

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In the span of less than a week, all of us are compelled  to practice social distancing. We can no longer hit the gym, or attend movies, concerts or sporting events. Eating out at restaurants and all social events are on hold. Children are no longer able to attend school. Many of us feel as if our lives have been turned upside down. All of that is understandable given the sudden nature of events. 

That said, we need to drop the panic mode and work together. During periods of social isolation we need to all do our part and remain positive. Uncertainty can be uncomfortable, but we can't allow that to stop us.

Below are a resources by two functional medicine practitioners. The first, a blog post written by Dr. Ben Weitz, DC of Weitz Chiropractic in Santa Monica, and a link to my latest Blog on COVID-19, Which you can READ HERE. Our aim is to give you our perspectives based on the knowledge we presently have with tools to move forward.

Coronavirus, what it is, and what to do about it. 

By Dr. Ben Weitz

If you’re watching the news reports all day while you are home from work, you can get completely panicked.  You may be thinking that the coronavirus will kill all of us, so you have to avoid contact with everyone and everything by staying in your house and dousing yourself and your pets and your house with bleach and alcohol.  In fact, you should bathe in bleach or alcohol.  You need to stockpile toilet paper and water and rice, beans, canned and frozen foods because there will be no food to eat or water to drink.  Or alternatively, you may think that the coronavirus is just a hoax from the fake news media to get President Trump out of office or it is just a mild flu that you should completely ignore. I have read up on some of the scientific reports about the coronavirus and would like to present a reasonable perspective on what the coronavirus is and how to keep yourself and your family safe without panic and fear.  Fear and anxiety will only weaken your immune system. 

First we will start with some of the basic facts.  

  1. What is the Coronavirus and what is Covid-19?

  • A virus is a tiny infectious organism that replicates inside of the cells of living organisms, including animals and plants and even bacteria.  

  • The coronavirus that is the cause of the current pandemic is a type of virus similar to the SARS (Severe Acute Respiratory Syndrome) virus that also started in China in November 2002 and spread around the world.  These are both coronaviruses that originated from bats.  

  • COVID-19 (Coronavirus disease 2019) is the disease caused by this current coronavirus.  Once the virus has infected you, it gets into your cells and starts reproducing unless your immune system can fight it off.  Because our immune system does not have antibodies to fight against this particular coronavirus it is referred to as a “Novel” virus, which is one of the reasons why it may be more dangerous than the seasonal flu.

  • COVID-19 is rapidly spreading and the rate in the US is likely to accelerate over the next few weeks, partially because we have just ramped up testing.  The social isolation measures we are taking are designed to slow down the spread and it is likely that the measures we are taking will lead to a leveling off and a slowing of new cases, though this might take several weeks or months.  But no matter how long it takes, we will get over this and 6 months or a year from now, things will be much better.  

  1. COVID-19 symptoms and incubation period.

  • After being infected, there is an incubation period of up to 14 days, which means that you may not have symptoms and still be infectious for up to 14 days.  This long incubation period is one reason why it is more likely to spread throughout society.  

  • One reason why you should not worry is that for 80% of those infected, they will have mild to moderate symptoms similar to the seasonal flu. 

  • Here are the most common symptoms in order of frequency:

    • Fever 

    • Cough 

    • Sore throat 

    • Runny or stuffy nose 

    • Body aches 

    • Headache 

    • Chills 

    • Fatigue

    • Sometimes vomiting and diarrhea

  1. How deadly is COVID-19?

While most (~80%) who contract the coronavirus will have mild symptoms, it appears to be more deadly than the seasonal flu by an order of at least 10 to 1.  The numbers out of China look like the fatality rate is between 3 and 4, while the rate in the US right now is between 1 and 2, but that is with many people with minor symptoms who have not gotten tested.   The more people who have had it will make the percentage who have died go down due to the math.   And we are only just rolling out our testing now, so there are many Americans who have been sick with COVID-19 and were sent home and have recovered and those numbers we don’t know now.  When the antibody tests are available, we will be able to get a sense of how many people previously had COVID-19 and recovered.

Those at biggest risk of severe symptoms like pneumonia are those with a weak or compromised immune system or who have existing heart or lung diseases.

 

  1. How is the coronavirus spread?  

While this virus is not airborne, it is spread through respiratory droplets, often produced while coughing or sneezing, which can then land on your face or hands or a nearby surface that you might touch, followed by touching your eyes, nose or mouth or some food or drink.  Once this virus lands on a surface, such as a countertop or a door handle it can live there for a few hours and possibly as long as 9 days, according to one study.   This is still being debated by the experts. 

  1. What is the best way to protect ourselves from getting Covid-19?

    1. Wash your hands for at least 20 seconds with soap and water.  The soap makes the fatty layer that surrounds the coronavirus fall apart.  Singing Happy Birthday twice is about 20 seconds.  Make sure to wash both the palm side and the back side of your hands and fingers. Wash under your fingernails and wash both thumbs. 

    2. Wash your hands multiple times per day, including after you blow your nose, cough, or sneeze. Also make sure to wash your hands after you have had close contact with others, after the bathroom, and before and after you eat.  You should also wash your hands before, during, and after preparing food, after you touch or feed your pet, and after visiting public spaces, such as stores.

    3. After washing your hands, drying them with a hand towel or paper towels is important, since you can remove germs with the friction.  

    4. If there is no soap and water, hand sanitizer or gel that contains at least 60% alcohol is your best bet.

    5. Clean and disinfect frequently touched surfaces, including doorknobs, light switches, desks, phone, keyboards, toilet seats, sinks, etc.

    6. Avoid shaking hands and instead use the elbow or forearm bump. and close contact with others except when necessary, such as going shopping, getting your hair cut, or going to your dentist or doctor.

    7. Avoid touching your face, rubbing your eyes, biting your nails, etc.

    8. If you have to cough or sneeze, do it into the crook of your elbow.

    9. Get chiropractic adjustments, which increase the likelihood that your nerves that start in your spinal cord and exit your spine in between vertebrae can flow freely.  Several scientific studies have shown increases in various measures of immune function with chiropractic adjustments.

  1. What not to do.

    1. There is no need to stock up on toilet paper or water. There is not going to be a lack of water. It is a viral infection, not a natural disaster.  There is no lack of toilet paper, except that too many people are hording it.  Calm down and stop worrying about stuff like this.  

    2. There is no need to horde food. There is plenty of food. Give the grocery stores a few days to stock their shelves and you will be able to get the food you need.  While some stores might be temporarily out of rice and beans and pasta and frozen foods, there is plenty of fresh fruits and vegetables, which is what much of your diet should consist of anyway.  Even if you must be isolated, you will still be allowed to go to the grocery store.

    3. Don’t watch the news before you go to bed or you may have trouble sleeping.  Read a book instead.

    4. Don’t stop exercising, even if gyms are closed, as they are in Los Angeles. Do pushups and bodyweight exercises, use bands and dumbbells, and go out for a walk.  Walk up a hill at a rapid pace.

    5. Did I mention not to spend too much time watching or reading the news?

  1. Ways to strengthen your immune system to help you fight off the coronavirus if you come into contact with it.  Since there is currently no effective treatment for COVID-19 and a vaccine is not available and it could be a year away or longer, the best way to protect yourself is by keeping your immune system strong.

    1. Make sure you get good sleep, since getting sufficient, quality sleep strengthens the immune system. 

    2. Continue to exercise regularly, since moderate levels of vigorous exercise improve immune function, including enhanced activity of macrophages, immunoglobulins, and anti-inflammatory cytokines.  If you are somebody who exercises by going to the gym like myself and your gym gets cancelled, you should find a way to exercise, such as by  

    3. Avoid sugar, processed foods, and junk food

    4. Eat foods that have immune boosting properties, like garlic, ginger, turmeric, onions, broccoli, mushrooms, citrus fruits, red peppers, and green tea.

    5. Drink plenty of clean, fresh water and don’t trust your tap water.  Your best bet is to get a water purification system, since plastic water bottles are problematic since chemicals from the plastic can leach into the water.

    6. Meditate 

    7. Listen to my Rational Wellness podcast (just kidding).

    8. There are a number of nutritional supplements and nutraceuticals that can benefit your immune system to help you fight off viruses, including the following favorites of mine:

      1. Vitamin C—take 500-1000 mg at least twice per day.  If you are sick take 100 mg every couple of hours. Reduce it if you get diarrhea.  Intravenous vitamin C may be beneficial in getting very high dosages into your system and there are several clinical studies using 12,000 to 24,000 mg/day IV vitamin C for patients with COVID-19

      2. Vitamin D is super important for your immune system and while it is best to get it from the sun, I have found that even in Southern California many patients have serum levels that are either low or less than the optimal level of 50-70 ng/mL. I have found 5000 IU per day to be a beneficial dosage for many patients, and ideally it should also contain vitamin K.

      3. N Acetyl-Cysteine is an antioxidant has been shown to help with acute respiratory diseases like COVID-19. I recommend 500-1000 mg twice per day. 

      4. Resveratrol and quercetin have both been shown to inhibit other types of coronavirus infections, so consider taking both of these. There is currently a clinical trial using quercetin in Wuhan for treatment of COVID-19.

      5. Selenium is a mineral that boosts the immune system. You can either eat 2-3 Brazil nuts or take a supplement of 200 mcg of selenium per day.

      6. Zinc has been shown to have antiviral effects, including against coronavirus. I recommend taking 15-20 mg twice per day for a month or two. If you do this for more than a few months, you should add 1-2 mg of copper.

      7. Reishi, shitaki, and other mushroom supplements contain beta glucans and are extremely potent immune strengtheners.  Check out episode 103 of my Rational Wellness podcast with mushroom expert Jeff Chilton.

      8. Probiotics are very important for immune function and there are even specific ones that are more potent for immune strengthening. 

      9. Andrographis, echinacea, elderberry, garlic, oregano, and astragalus are some of my favorite immune strengthening herbs that have activity against viruses.

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NEW HOPE FOR LOWERING LP(a)

Lipoprotein (a) or simply Lp(a) levels , are genetically determined.  When elevated they are a risk factor for both coronary disease and aortic stenosis. This is no small problem, because as many as 20% of the population is affected. As an integrative cardiologist, I measure Lp(a) levels in essentially all my patients with abnormal lipids, which include both cholesterol and triglyceride levels. In my patients who have experienced a cardiac event such as a heart attack or stroke, or have received balloon angioplasty/ stent or bypass surgery, this measurement is even more crucial.

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Up until now, there have been no effective treatments. Statins may work well in lowering LDL cholesterol, but they do nothing to lower Lp(a). Exercise and diet also play no role. It’s simply genetic and lifestyle measures do nothing.

That is until now! An investigational drug targeting LPA gene expression successfully reduced levels of Lp(a) . This was a modest study comprising 286 patients, but it was double-blinded, and placebo controlled. Lp(a) lowering was dose dependent and observed as early as the first month of therapy. The study was led by investigators at UCSD and Ionis Pharmaceuticals.

The 80% reduction in Lp(a) levels would be expected to have a major impact over currently available therapies . For years I have used niacin in relatively high doses to lower Lp(a) levels. However, I have often noted varying success.

Drugs are no panacea. This drug will be expensive and not without potential side effects. However, the ability to lower Lp(a) levels in a large cohort of patients where lifestyle management is ineffective  will hopefully affect outcomes in a positive way.

You can read the original article from MedPageToday by clicking HERE.

Source Reference: Zheng B, et al "Insomnia symptoms and risk of cardiovascular diseases among 0.5 million adults: A 10-year cohort" Neurology 2019; DOI:10.1212/WNL.0000000000008581.

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DANGER IN INSOMNIA & SLEEP DEPRIVATION

We are becoming increasingly aware of the importance of sleep in maintaining our overall health and wellness. Adequate sleep is essential to repair and restore our organ systems such as our muscles and immune system.  It’s vital for memory, creativity and quality of life. Sleep helps to curb inflammation while helping us maintain a healthy weight.

A recent observational study of a half million people in China linked insomnia to higher rates of heart attacks and strokes. Interestingly enough this was most apparent in younger adults who had normal blood pressure.

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Three insomnia symptoms were studied: trouble falling asleep or staying asleep, awakening too early, and daytime dysfunction related to poor sleep.

The research supports our current knowledge about the contribution of impaired sleep for both cardiovascular and cerebrovascular disease.

The information gleaned from this study is extremely useful, but there are limitations to consider; insomnia symptoms were self-reported and were assessed only at baseline. Like many observational studies, association but not necessarily causation can be claimed.

You can read the original article from MedPageToday by clicking HERE.

Source Reference: Zheng B, et al "Insomnia symptoms and risk of cardiovascular diseases among 0.5 million adults: A 10-year cohort" Neurology 2019; DOI:10.1212/WNL.0000000000008581.

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CALORIC RESTRICTION WINS

It is common knowledge that most of us eat more than we actually need. It has also become increasingly more apparent that fasting on one level or another brings a myriad of benefits. A recent study from Duke University demonstrated that caloric restriction helped improve all factors of metabolic syndrome in patients without obesity. (CALORIE trial)

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This was a very modest restriction, a 12% reduction or 300 fewer calories a day. Following this plan for 2 years, there were significant improvements in multiple cardiovascular risk factors:

  • Systolic blood pressure

  • Diastolic blood pressure

  • LDL or the “lousy” cholesterol

  • Total cholesterol to HDL “healthy” cholesterol ratio

  • Triglycerides

Other benefits include lowering of fasting insulin, fasting blood sugar and C-reactive protein (a sensitive measure of inflammation).

Considered groundbreaking, this is the first long-term caloric restriction intervention in non-obese young and middle age subjects. Furthermore, there was a very low dropout rate, which connotes that a modest restriction in calories is doable.

I find this study very exciting but not surprising. The benefits of restricted caloric intake go way beyond cardiovascular health. This strategy is being studied for extending lifespan and anti-aging in general.  

Read Original Article HERE

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The Medical Advocate at Santa Monica Public Library
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Dr. Elkin, known as The Medical Advocate, will be presenting to the Functional Medicine Discussion Group of Santa Monica at the Santa Monica Public Library at 6:30 pm on June 27, 2019.

As an integrative cardiologist, Dr. Elkin will address how to best stratify one’s cardiac risk using the latest in cutting edge laboratory testing. After all, it’s not merely how low the cholesterol numbers are, but one’s actual risk  of contracting a heart attack or stroke 

Emphasis will be on lifestyle, a healthy diet of the 21st century, and appropriate supplementation.

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First-Ever Study: Grounding Patients with Hypertension Improves Blood Pressure

A Press Release by prnewswire.com on my Earthing Case Study was sent out recently and I want to share it with you!

WHITTIER, Calif., March 6, 2019 /PRNewswire/ -- A novel study by a Southern California cardiologist has shown for the first time that Planet Earth's own natural energy has the potential to help reduce high blood pressure.

The study tested the lifestyle concept of grounding, also known as Earthing − the discovery that contact with the Earth's natural, subtle electric charge can lower pain and stress.  You can ground yourself by spending time barefoot outdoors on natural surfaces, like grass, soil, gravel, stone, and sand, and indoors using special conductive mats and patches while sitting or sleeping.

The study, appearing in the journal Alternative Therapies in Health and Medicine, involved 10 participants with various degrees of hypertension and trouble controlling blood pressure. Multiple measurements over several months while they were grounded resulted in significant improvement of blood pressure and better control, in many cases well within that time frame. 

The participants slept grounded and grounded themselves for several more hours during the day.  Subjectively, they reported better sleep, more calmness, and less aches and pains. 

According to the Earthing Institute, an online resource for grounding information, grounding restores a healing energetic connection with the Earth lost over time due to human lifestyle, such as living/working elevated off the ground and wearing synthetic soled shoes that block the Earth's energy underfoot.  

Grounding may improve blood pressure in a variety of ways:  

- A calming effect on the nervous system.

- A normalizing effect on the stress hormone cortisol.

- Reduction of inflammation and pain.

- Better sleep.

- Improved blood flow.

The study was inspired by anecdotal feedback describing a lowering of high blood pressure after people start grounding.  

"The objective was to test the validity of such reports by measuring blood pressure among grounded hypertensive patients over time," says integrative cardiologist Howard Elkin, M.D., who practices in Whittier and Santa Monica, California.  "The study, although small in size, gives a glimpse as to the possibility that grounding may be a simple lifestyle strategy for improving blood pressure. Obviously, larger studies are needed to definitively validate such an effect for hypertensive patients. This is a first step."

Hypertension carries serious health risks, including heart attack, stroke, and kidney disease, and affects some 75 million American adults (U.S. Centers for Disease Control and Prevention).

Source: www.earthinginstitute.net 
Dr. Elkin's office, 1-562-945-3753, https://www.heartwise.com/ 
To view the study, click here.  Read additional grounding research, here   
Questions on grounding, info@earthinginstitute.net 

Grounding Patients With Hypertension Improves Blood Pressure: A Case History Series Study

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Howard Elkin MD